ChemBK
  • Home
  • Product Category

Isobutyl paraben

isobutyl 4-hydroxybenzoate

CAS: 4247-02-3

Molecular Formula: C11H14O3

  1. Home
  2. Product Category
  3. food additives
  4. preservative
  5. Isobutyl paraben

Isobutyl paraben - Names and Identifiers

Name isobutyl 4-hydroxybenzoate
Synonyms Isobutylparaben
Isobutyl paraben
iso-Butyl Paraben
isobutyl 4-hydroxybenzoate
Isobutyl-P-Hydroxybenzoate
2-Methylpropyl 4-hydroxybenzoate
4-Hydroxybenzoic acid isobutyl ester
CAS 4247-02-3
EINECS 224-208-8
InChI InChI=1/C11H14O3/c1-8(2)7-14-11(13)9-3-5-10(12)6-4-9/h3-6,8,12H,7H2,1-2H3

Isobutyl paraben - Physico-chemical Properties

Molecular FormulaC11H14O3
Molar Mass194.23
Density1.105g/cm3
Melting Point76°C
Boling Point302.3°C at 760 mmHg
Flash Point125.4°C
Water SolubilityInsoluble in water.
Solubility Insoluble in water (0.035g/100ml,25°C). Soluble in ethanol, glacial acetic acid, propylene glycol and acetone.
Vapor Presure0.000556mmHg at 25°C
AppearanceShape neat, color White
pKa8.17±0.15(Predicted)
Storage Condition2-8°C
Refractive Index1.524
MDLMFCD00020167
Physical and Chemical PropertiesChemical properties colorless fine crystals or white crystalline powder. No smell. Insoluble in water (0.035g/100ml,25 ℃). Soluble in ethanol, glacial acetic acid, propylene glycol and acetone.
UseUse preservative; anti-mold agent. It is rarely used alone, often mixed with isopropyl ester, butyl ester, etc., as an oil-in-water emulsifier. The solubility of butyl ester is increased by 2~3 times. Easy to use in soy sauce.

Isobutyl paraben - Risk and Safety

Risk Codes51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
UN IDsUN 3077 9/PG 3
WGK Germany2
RTECSDH2247000
HS Code29182900
Hazard ClassIRRITANT

Isobutyl paraben - Upstream Downstream Industry

Raw MaterialsHydrochloric acid
2-Methyl-1-propanol
4-Hydroxybenzoic acid
4-Hydroxyphenylacetic acid
GLOBULINS, CAT GAMMA

Isobutyl paraben - Nature

Solubility Chloroform (Slightly), Methanol (Slightly)
BRN 2642305
Last Update：2024-04-09 20:45:29

Isobutyl paraben - Uses and synthesis methods

overview

preservative isobutyl paraben, also known as p-hydroxybenzoate, has the advantages of high efficiency, low toxicity, broad spectrum, easy compatibility, etc., so in addition to being the mainstream food preservative in many developed countries, It is also widely used in daily chemical, pharmaceutical and feed industries.

application

Isobutyl paraben, also known as p-hydroxybenzoate, has a good antibacterial effect on food molds, yeasts and bacteria, destroys the cell membrane of microorganisms, denatured proteins in the cell, and inhibits the activity of the cell's respiratory enzyme system and electron transport enzyme system, and the antibacterial effect has a good effect in a wide pH range. Therefore, it is widely used in food, feed, cosmetics, daily chemicals and medicine industries. It is a safe and effective preservative used internationally and one of the key food preservatives in my country.

identification test

is the same as 1 and 2 in the "ethyl p-hydroxybenzoate (07009)" identification test.

content analysis

Same as "ethyl p-hydroxybenzoate (07009)" method. However, the sample does not need to be pre-dried. Each mL lmol/L sodium hydroxide solution is equivalent to 194.2mg of isobutyl p-hydroxybenzoate (C11H14O3).

Toxicity

LD508.39g/kg (rat, oral).

use limited

the maximum usage amount stipulated in Japan (calculated as p-hydroxybenzoic acid, 1g is equivalent to 0.711lg p-hydroxybenzoic acid, g/kg)(this product/g): soy sauce 0.25g/L (0.35 of this product); Edible vinegar 0.1g/L (0.14 of this product); Cool drinks and syrup 0.1 (0.14 of this product); Fruit seasoning sauce 0.2 (0.28 of this product); Fruit and vegetable 0.012 (0.016 of this product).

Production method

1. It is obtained by esterification of p-hydroxybenzoic acid and isobutanol. The esterification reaction is carried out in the presence of sulfuric acid, using benzene or toluene as solvent, heating and reflux reaction to obtain isobutyl p-hydroxybenzoate. According to the "Japanese Food Additives Public Agreement", the purity of the product should be above 99%. The toxicity of the product is relatively small, and the oral LD50 of mice is 8.38 g/kg.

2. It is obtained by heating and refluxing p-hydroxybenzoic acid and isobutanol in the presence of sulfuric acid with an azeotropic solvent such as benzene or toluene.

Last Update：2024-04-09 20:49:11
Isobutyl paraben
Supplier List
Wuhan UCchem Biotechnology Co., LTD
Spot supply
Product Name: Isobutylparaben Request for quotation
CAS: 4247-02-3
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148 Click to send a QQ messageSend QQ message
Wechat: 18162425036
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: isobutyl 4-hydroxybenzoate Request for quotation
CAS: 4247-02-3
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: isobutyl 4-hydroxybenzoate Request for quotation
CAS: 4247-02-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Isobutyl 4-Hydroxybenzoate Visit Supplier Webpage Request for quotation
CAS: 4247-02-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Zouping Mingxing Chemical Co., Ltd.
Product Name: Isobutyl 4-hydroxybenzoate Request for quotation
CAS: 4247-02-3
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987 Click to send a QQ message
Wechat: 13605431940
WhatsApp: 13605431940
Wuhan UCchem Biotechnology Co., LTD
Spot supply
Product Name: Isobutylparaben Request for quotation
CAS: 4247-02-3
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148 Click to send a QQ messageSend QQ message
Wechat: 18162425036
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: isobutyl 4-hydroxybenzoate Request for quotation
CAS: 4247-02-3
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: isobutyl 4-hydroxybenzoate Request for quotation
CAS: 4247-02-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Isobutyl 4-Hydroxybenzoate Visit Supplier Webpage Request for quotation
CAS: 4247-02-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Zouping Mingxing Chemical Co., Ltd.
Product Name: Isobutyl 4-hydroxybenzoate Request for quotation
CAS: 4247-02-3
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987 Click to send a QQ message
Wechat: 13605431940
WhatsApp: 13605431940
View History
Isobutyl paraben
Raw Materials for Isobutyl paraben
Hydrochloric acid
2-Methyl-1-propanol
4-Hydroxybenzoic acid
4-Hydroxyphenylacetic acid
GLOBULINS, CAT GAMMA
  • Home
  • Product Category

© 2015, 2023 ChemBK.com All Rights Reserved | Build: 20230617001